The Riddle of the Bamboo Annals

The COMPare project sets out to address the problem of outcome switching in clinical trials. In advance of our first academic publication on the project, consistent with our open data approach, we are now beginning to share the responses we have had from journals. We think they provide important qualitative information on the reasons why this problem has persisted for so long. Other journals have not responded in the same way. This blog post is about a long response to COMPare written by the editors of Annals [1], after we sent a series of correction letters on trials misreported in that journal. The editors have published their own response as a letter in the online edition of the journal, and it will soon appear in the paper edition, alongside some of our letters. We believe their response reveals a set of important misunderstandings about the issue of outcome switching, from the editors of the 4 th highest impact factor journal in medicine. We are waiting to hear if they will print it. Throughout their comment the editors seem confused on this key issue. They argue that they should be entitled to permit undeclared outcome switching on the pages of Annals according to their own skilful judgement.

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Rosemary Kay , August 25, — Digital. This project highlighted the barrier that digital poverty had on both care providers and residents who would benefit from technology in the home, but did not have access to affordable connectivity. That is where the issue lies. With the new normal comes new responsibilities. Whether it is a crafts session with an emerging artist or a live music concert in a city centre library — libraries know how to create a… Read More Stonehenge: Meeting new challenges at the ancient monument Jennifer Davies , August 20, — Enjoy Summer Safely.

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Since the establishment of the Journal of Medical Case Reports in , the number of journals that publish case reports has increased rapidly, and most of these journals are open access. Open access publishing usually requires authors to pay publication fees while offering the articles online, free of charge, and free of most copyright and licensing restrictions.

The movement for open access has gained support in the research community, with the publishers BioMed Central and PLOS ONE becoming leaders in scientific publishing in their number of articles and citations. As the number of open access publishers has exploded, so too has the number of publishers that act in bad faith to profit from the open access model. Simple guidelines have been developed and resources are available to help authors choose a suitable journal for publication of their case reports.

Case reports offer unique value to the body of medical knowledge by describing new diseases, disease mechanisms, therapeutic approaches, and adverse or beneficial effects of drugs. The act of recording, discussing with colleagues, and publishing clinical observations as case reports remains essential to the art of medicine and patient care [ 1 ]. These short communications generate or enforce hypotheses that may lead to further evaluation in larger study designs [ 2 ].

In providing detailed descriptions of the symptoms, signs, diagnosis, treatment, and follow-up of an individual patient, case reports reflect clinical experience and support medical progress. By design, the format lacks statistical sampling, placing it at the bottom of the hierarchy of clinical evidence. Case reports do not include controls, have limited sample size one to a few individuals , and are unblinded, limitations that require a cautious approach to interpretation of findings.

General medical journals publish case reports sparingly, often only publishing those that provide new information on adverse events that can be linked to an intervention [ 3 , 4 ]. The merits of large randomized studies are well known, but many clinicians recognize the value of case reports as a complement to evidence-based medicine.

FDA promises crackdown on researchers who fail to properly register and report studies

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Arthropod Management Tests formerly Insecticide and Acaricide Tests is an editor-reviewed publication that publishes short reports on preliminary and routine screening tests for management of arthropods Explore the archive. Publishing in an open access journal makes your article freely accessibly to a broad, global, interdisciplinary audience in a user-friendly digital medium immediately upon publication. Learn more. Learn how to submit your research. Register to receive alerts as soon as new content is published from Arthropod Management Tests.

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Taming the SRU. The patient is a male in his thirties with a past medical history of Human Immunodeficiency Virus HIV who presents to the emergency department ED with a rash and eye pain. The rash has been present for the past six weeks and started as red spots on the trunk that spread to the extremities, including his palms and soles. The rash is neither pruritic nor painful, and recently his hands have begun to peel.

He denies new sexual or environmental exposures. For the past week, he has been taking oral prednisone that was prescribed by his primary care provider, but his rash has not improved. The patient also reports bilateral eye pain.

Where does Annals of Internal Medicine stand on outcome switching? A detailed response.

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The Annals of %spdate% Refuted or another misfortune,” the F.T.C. defined in a blog publish this week. utilizing an internet service and chatting to individuals from all over the world. There are a couple of indicators you should look out for when taking a look at a possible match’s on-line dating profile.

This book is the result of discoveries made by Nivison beginning in It uses critically without superseding his monographs from through , combined with his discoveries through Its main thrust is to show that the methods and results of the PRC “Three Dynasties Project” are invalid, and that recovering chronology before BCE can be solved only by using the supposedly spurious Jinben Zhushu Jinian “Modern Text” Bamboo Annals , combined with the hypothesis that reign lengths of record were normally the years after completion of mourning for the preceding king.

Part One presents resulting exact dates from the beginning of Xia, confirmed by discoveries in astronomy by D. Pankenier and Kevin Pang. Part Two criticizes the Three Dynasties Project and argues for the post-mourning hypothesis and the high antiquity of the three-years mourning institution. In Part Three, applying a discovery by E.

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